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N-[2-[[6-[(1-Acetyl-4-piperidinyl)amino]-9-[(2R,3R,4S,5S)-5-(3-ethyl-5-isoxazolyl)tetrahydro-3,4-dihydroxy-2-furanyl]-9H-purin-2-yl]amino]ethyl]guanidine

(2R,3R,4S,5S)-2-[2-[(trans-4-Aminocyclohexyl)amino]-6-[(tetrahydro-1,1-dioxido-2H-thiopyran-4-yl)amino]-9H-purin-9-yl]-5-(3-ethyl-5-isoxazolyl)tetrahydro-3,4-furandiol

(2S,3S,4R,5R)-2-(3-Ethyl-5-isoxazolyl)tetrahydro-5-[2-[[2-(1-piperidinyl)ethyl]amino]-6-[(tetrahydro-1,1-dioxido-2H-thiopyran-4-yl)amino]-9H-purin-9-yl]-3,4-furandiol

(2S,3S,4R,5R)-2-(3-Ethyl-5-isoxazolyl)tetrahydro-5-[2-[[2-(2-pyridinyl)ethyl]amino]-6-[(tetrahydro-2H-thiopyran-4-yl)amino]-9H-purin-9-yl]-3,4-furandiol

1-[4-[[2-[(trans-4-Aminocyclohexyl)amino]-9-[(2R,3R,4S,5S)-5-(3-ethyl-5-isoxazolyl)tetrahydro-3,4-dihydroxy-2-furanyl]-9H-purin-6-yl]amino]-1-piperidinyl]ethanone

1-[4-[[9-[(2R,3R,4S,5S)-5-(3-Ethyl-5-isoxazolyl)tetrahydro-3,4-dihydroxy-2-furanyl]-2-[[(1S)-1-(hydroxymethyl)-2-phenylethyl]amino]-9H-purin-6-yl]amino]-1-piperidinyl]ethanone

2-[[9-[(2R,3R,4S,5S)-5-(3-Ethyl-5-isoxazolyl)tetrahydro-3,4-dihydroxy-2-furanyl]-2-[[(1S)-1-(hydroxymethyl)-2-phenylethyl]amino]-9H-purin-6-yl]amino]-N-methylethanesulfonamide

N-[2-[[9-[(2R,3R,4S,5S)-5-(3-Ethyl-5-isoxazolyl)tetrahydro-3,4-dihydroxy-2-furanyl]-6-[(tetrahydro-1,1-dioxido-2H-thiopyran-4-yl)amino]-9H-purin-2-yl]amino]ethyl]guanidine

2-[[2-[[2-[(Aminoiminomethyl)amino]ethyl]amino]-9-[(2R,3R,4S,5S)-5-(3-ethyl-5-isoxazolyl)tetrahydro-3,4-dihydroxy-2-furanyl]-9H-purin-6-yl]amino]-N-methylethanesulfonamide

N-[2-[[6-[(2,2-Diphenylethyl)amino]-9-[(2R,3R,4S,5S)-5-(3-ethyl-5-isoxazolyl)tetrahydro-3,4-dihydroxy-2-furanyl]-9H-purin-2-yl]amino]ethyl]guanidine

(2R,3R,4S,5S)-2-[6-[(2-Cyclohexylethyl)amino]-2-[[(1S)-1-(hydroxymethyl)-2-phenylethyl]amino]-9H-purin-9-yl]-5-(3-ethyl-5-isoxazolyl)tetrahydro-3,4-furandiol

(2R,3R,4S,5S)-2-[6-[(2-Cyclohexylethyl)amino]-2-[[2-(1-methyl-1H-imidazol-4-yl)ethyl]amino]-9H-purin-9-yl]-5-(3-ethyl-5-isoxazolyl)tetrahydro-3,4-furandiol

(2S,3S,4R,5R)-2-(3-Ethyl-5-isoxazolyl)tetrahydro-5-[6-[[(3-iodophenyl)methyl]amino]-2-[[2-(1-methyl-1H-imidazol-4-yl)ethyl]amino]-9H-purin-9-yl]-3,4-furandiol

(2R,3R,4S,5S)-2-[2-[(trans-4-Aminocyclohexyl)amino]-6-[(2,2-diphenylethyl)amino]-9H-purin-9-yl]-5-(3-ethyl-5-isoxazolyl)tetrahydro-3,4-furandiol

4-[2-[[6-Amino-9-[(2R,3R,4S,5S)-5-(3-ethyl-5-isoxazolyl)tetrahydro-3,4-dihydroxy-2-furanyl]-9H-purin-2-yl]amino]ethyl]benzenesulfonamide

(2R,3R,4S,5S)-2-[6-[(2,2-Diphenylethyl)amino]-2-[[(1S)-1-(hydroxymethyl)-2-phenylethyl]amino]-9H-purin-9-yl]-5-(3-ethyl-5-isoxazolyl)tetrahydro-3,4-furandiol

(2R,3R,4S,5S)-2-[6-[(2,2-Diphenylethyl)amino]-2-[[2-(2-pyridinylamino)ethyl]amino]-9H-purin-9-yl]-5-(3-ethyl-5-isoxazolyl)tetrahydro-3,4-furandiol

(2S,3S,4R,5R)-2-(3-Ethyl-5-isoxazolyl)tetrahydro-5-[2-[[(1S)-1-(hydroxymethyl)-2-phenylethyl]amino]-6-[(tetrahydro-2H-pyran-4-yl)amino]-9H-purin-9-yl]-3,4-furandiol

(2S,3S,4R,5R)-2-(3-Ethyl-5-isoxazolyl)tetrahydro-5-[2-[[2-(1-piperidinyl)ethyl]amino]-6-[(tetrahydro-2H-pyran-4-yl)amino]-9H-purin-9-yl]-3,4-furandiol

(2S,3S,4R,5R)-2-(3-Ethyl-5-isoxazolyl)tetrahydro-5-[2-[[2-(2-pyridinyl)ethyl]amino]-6-[(tetrahydro-2H-pyran-4-yl)amino]-9H-purin-9-yl]-3,4-furandiol

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